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The lab of anti-aging focuses on solving the mysteries of aging, zinc biology, and mammalian sugar transporters, and on the development of novel applied biomaterials

Representative Journals  

The Slc45a4 Gene Regulates Pigmentation in a Manner Distinct from that of the OCA4 Gene Slc45a2.

J Invest Dermatol. 2024 Mar;144(3):720-722.

The epithelial zinc transporter ZIP10 epigenetically regulates human epidermal homeostasis by modulating histone acetyltransferase activity.

Br J Dermatol. 2019 Apr;180(4):869-880. (#1 Research Journal in Dermatology from 2020) 

Requirement of zinc transporter ZIP10 for epidermal development: implication of the ZIP10-p63 axis in epithelial homeostasis.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12243-12248. Cover Image 

Requirement of Zinc Transporter SLC39A7/ZIP7 for Dermal Development to Fine-Tune Endoplasmic Reticulum Function by Regulating Protein Disulfide Isomerase.

J Invest Dermatol. 2017 Aug;137(8):1682-1691. (#1 Research Journal in Dermatology by 2019) 

An acrodermatitis enteropathica-associated Zn transporter, ZIP4, regulates human epidermal homeostasis.

J Invest Dermatol. 2017 Apr;137(4):874-883. (#1 Research Journal in Dermatology by 2019) 

Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression.

PLoS Genet. 2017 Aug 30;13(8):e1006950. 

ITAC induces the melanocytic migration and hypopigmentation through destabilizing p53 via HDAC5: A possible role of ITAC in pigment-related disorders.

Br J Dermatol. 2017 Jan;176(1):127-137. 

Fibronectin-Containing Extracellular Vesicles Protect Melanocytes Against Ultraviolet Radiation-Induced Cytotoxicity.

J Invest Dermatol. 2016 May;136(5):957-66. (#1 Research Journal in Dermatology) 

Jak1 tyrosine kinase hyperactivation induces stepwise progressive pruritic dermatitis.

J Clin Invest. 2016 Jun 1;126(6):2064-76. doi: 10.1172/JCI82887. Epub 2016 Apr 25. 

Molecular pathogenesis of Spondylocheirodysplastic Ehlers-Danlos syndrome caused by mutant ZIP13 proteins.

EMBO Mol Med. 2014 Jul 9;6(8):1028-42. 

The zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B cell receptor signal strength.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11786-91. 

The zinc transporter SLC39A10/ZIP10 facilitates anti-apoptotic signaling during early B cell development.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11780-5.

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