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Scientific Articles

66. The Slc45a4 Gene Regulates Pigmentation in a Manner Distinct from that of the OCA4 Gene Slc45a2.

Brito S, Heo H, Cha B, Lee SH, Park G, Kwak BM, Seong JK, Lee H, Park JH, Weon BM, Bin BH*

J Invest Dermatol. 2024 Mar;144(3):720-722

65. A systematic exploration of ginsenoside Rg5 reveals anti-inflammatory functions in airway mucosa cells.

Heo H, Kim Y, Cha B, Brito S, Kim H, Kim H, Fatombi BM, Jung SY, Lee SM, Lei L, Lee SH, Park G, Kwak BM*, Bin BH*, Park JH*, & Lee MG*.

J Ginseng Res. 2023 Jan; 47(1), 97-105.

64. The Protective Effects of Moisturizer ContainingPotentilla anserina Extract in the Topical Treatment of SkinDamage Caused by Masks.

Choi H, Ha JH, Kang HC, Seo WS, Bin BH*

Int J Mol Sci. 2023 Sep 19;24(18):14294. 

63. Development of Vegetable Alternative Materials for Mink Oil

Seok-ju Lee , 김민태 ( Min-tae Kim ) , 이소민 ( So Min Lee ) , 정소영 ( So Young Jung ) , ( Sofia Brito ) , 허효진 ( Hyojin Heo ) , 차병선 ( Byungsun Cha ) , 이상훈 ( Sang Hun Lee ) , ( Lei Lei ) , 조하현 ( Ha Hyeon Jo ) , 천유연 ( You-yeon Chun ) , 김예지 ( Ye Ji Kim ) , 이미기 ( Mi-gi Lee ) , 곽병문 ( Byeong-mun Kwak ) , 빈범호 ( Bum-ho Bin )

DOI: JKWST Vol.49(No.1) 1-8, 2023

62 Antioxidant and Whitening Effect of Crocus chrysanthus (Herb.) Herb. Bulb Extracts

유경완 Kyung Wan Yoo , 이소민 ( So Min Lee ) , 정소영 ( So Young Jung ) , 허효진 ( Hyojin Heo ) , 차병선 ( Byungsun Cha ) , ( Sofia Brito ) , ( Lei Lei ) , 이상훈 ( Sang Hun Lee ) , 천유연 ( You-yeon Chun ) , 조하현 ( Ha Hyeon Jo ) , 김예지 ( Ye Ji Kim ) , 이미기 ( Mi-gi Lee ) , 곽병문 ( Byeong-mun Kwak ) , 빈범호 ( Bum-ho Bin )

DOI: JKWST Vol.49(No.1) 39-46, 2023

61 Manufacture and Characteristics of Peel-off Pack for Natural Cosmetics Using Pullulan and Polysaccharides

곽준수 Jun Soo Kwak , 정소영 ( So Young Jung ) , 이소민 ( So Min Lee ) , 이석주 ( Seok-ju Lee ) , ( Sofia Brito ) , 차병선 ( Byungsun Cha ) , 허효진 ( Hyojin Heo ) , ( Lei Lei ) , 이상훈 ( Sang Hun Lee ) , 조하현 ( Ha-hyeon Jo ) , 천유연 ( You-yeon Chun ) , 김예지 ( Ye Ji Kim ) , 김형묵 ( Hyung Mook Kim ) , 이미기 ( Mi-gi Lee ) , 곽병문 ( Byeong-mun Kwak ) , 빈범호 ( Bum-ho Bin )

DOI: JKWST Vol.49(No.1) 67-74, 2023

60 Study on Stabilization of Retinaldehyde using Drug-in-Cyclodextrinin- Liposome (DCL) for Skin Wrinkle Improvement

하지훈 Ji Hoon Ha , 최형 ( Hyeong Choi ) , 홍인기 ( In Ki Hong ) , 한상근 ( Sang-kuen Han ) , 빈범호 ( Bum Ho Bin )

DOI: JKWST Vol.48(No.1) 77-85, 2022

59 A Study on the High Content Ceramide Stabilization Formulation with Cyclodextrin8 

김예지 Ye Ji Kim , 한상우 ( Sang Woo Han ) , 이소민 ( So Min Lee ) , 차병선 ( Byungsun Cha ) , 허효진 ( Hyojin Heo ) , ( Sofia Brito ) , ( Lei Lei ) , 이상훈 ( Sang Hun Lee ) , 천유연 ( You-yeon Chun ) , 조하현 ( Ha Hyeon Jo ) , 김형묵 ( Hyung Mook Kim ) , 곽병문 ( Byeong-mun Kwak ) , 빈범호 ( Bum-ho Bin )

DOI: JKWST Vol.49(No.2) 97-106, 2023

58 Development of Transparent Cleansing Water with Salicylic Acid and Capryloyl Salicylic Acid

여혜림 Hye Lim Yeo , 박인정 ( Injeong Park ) , 정소영 ( So Young Jung ) , 이소민 ( So Min Lee ) , 김형묵 ( Hyung Mook Kim ) , 이미기 ( Mi-gi Lee ) , 곽병문 ( Byeong-mun Kwak ) , 빈범호 ( Bum-ho Bin )

DOI: JKWST Vol.48(No.2) 87-95, 2022

57. Evaluation of the Potential of Cellobiose as a Material for Whitening Cosmetics based on Autophagy and Melanin Production Efficacy in Melanocytes

차병선 Byungsun Cha , 이석주 ( Seok Ju Lee ) , ( Sofia Brito ) , 정소영 ( So Young Jung ) , 이소민 ( So Min Lee ) , ( Lei Lei ) , 이상훈 ( Sang Hun Lee ) , ( Zubaidah Al-khafaji ) , 빈범호 ( Bum-ho Bin ) , 곽병문 ( Byeong-mun Kwak ) , 허효진 ( Hyojin Heo )

DOI: JKWST Vol.48(No.4) 365-372, 2022

 

56. Zinc and Zinc Transporters in Dermatology.

Al-Khafaji Z, Brito S,  Bin BH*

Int J Mol Sci. 2022 Dec 18;23(24):16165.

55. A systematic exploration reveals the potential of spermidine for hypopigmentation treatment through the stabilization of melanogenesis-associated proteins.

Brito S, Heo H, Cha B, Lee SH, Chae S*, Lee MG*, Kwak BM*, Bin BH*

Sci Rep. 2022 Aug 25;12(1):14478.

54. Evaluation of the Poteintial of Nitrogen Plasma to Cosmetics.

Lee SM, Jung SY, Brito S, Heo H, Cha BS, Lei L, Lee SH, Lee MG*, Bin BH* & Kwak BM*

J Soc Cosmet Sci Korea. Vol 48 No 3 September 2022, 189-196.

53. Human milk oligosaccharide 2'-fucosyllactose promotes melanin degradation via the autophagic AMPK–ULK1 signaling axis.

Heo H, Cha B, Jang D, Park C, Park G, Kwak BM, Bin BH*, Park JH* & Lee MG*

Sci Rep. 2022 Sep 20;12(1):15711.

52. Development of Transparent Cleansing Water with Salicylic Acid and Capryloyl Salicylic Acid.

Yeo HL, Park IJ, Jung SY, Lee SM, Kim HM, Lee MG*, Bin BH* & Kwak BM*

J Soc Cosmet Sci Korea. Vol 48 No 2 June 2022, 87-95.

51. A Study on Melanin Reduction through Autophagy by 2'-Fucosyllactose

Jung SY, Yu HJ, Heo H, Lee SM, Brito S, Cha BS, Lei L, Lee SH, Bin BH*, Lee MG* & Kwak BM*

J Soc Cosmet Sci Korea. Vol 48 No 2 June 2022, 105-112.

​49. Nicotinamide mononucleotide reduces melanin production in aged melanocytes by inhibiting cAMP/Wnt signaling. 

Brito S, Baek JM, Cha B, Heo H, Lee SH, Lei L, Jung SY, Lee SM, Lee SH, Kwak BM, Chae S*, Lee MG* & Bin BH*.

J Dermatol Sci. 2022 Jun;106(3):159-169.

48. 320 Pesticides Analysis of Essential Oils by LC-MS/MS and GC-MS/MS

오가향 Ka Hyang Oh , 박성막 ( Sung Mak Park ) , 이소민 ( So Min Lee ) , 정소영 ( So Young Jung ) , 곽병문 ( Byeong-mun Kwak ) , 이미기 ( Mi-gi Lee ) , 이미애 ( Mi Ae Lee ) , 최성민 ( Sung Min Choi ) , 빈범호 ( Bum-ho Bin )

Vol.47(No.4) 317-331, 2021

47. Skin Anti-aging and Anti-wrinkle Effects of Pinus koreaiensis Seed Oil.

Kim HM, Kim TJ, Im DB, Ha SB, Kim EH, Cha BS, Jeo HJ, Brito S, Lee YM, Bin BH & Kwak BM*

J Korean Med Ophthalmol Otolaryngol Dermatol. 2021; 34(4):1-11.

46. Development of Gel Sheet Mask Based on Physical Properties Study of Tamarindus indica Seed Gum, Ethanol, Polyols, and Acid/Base Reaction.

Yeo HL, Lee HJ, Kang HR, Jung SY, Lee SM, Kim HM, Kwak BM, Lee MG, Bin BH*

J Soc Cosmet Sci Korea. Vol 47 No 4 December 2021, 305-316.

45. Application of Oryza sativa (Rice) Bran Oil as an Anti-pollution Cosmetic Material. 

Kang HR, Jung SY, Heo H, Cha B, Brito S, Lee SM, Yeo HL, Yoo KW, Kwak JS, Kwak BM, Lee MG* & Bin BH*

J Soc Cosmet Sci Korea. Vol. 47 No 3 September 2021, 237-245.

44.  Application of Nanoparticles Derived from Artemisia princeps for Cosmetic Products.

Jung SY., Kang HR, Yoo HJ, Choi H, Heo H, Cha B, Brito S, Lee SM, Yeo HL, Kang SJ, Lee DY, Kwak BM, Lee MG* & Bin BH*

J Soc Cosmet Sci Korea. Vol. 47 No 3 September 2021, 265-271.

43. Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation.

Jo H, Brito S, Kwak BM, Park S*, Lee MG*, & Bin BH* 

Int J Mol Sci. 22(5), 2410.

42. Topical Delivery of Nanosized Hydroxycitric Acid Enriched Extract-Loaded Ethosomes for Suppression of Lipid Droplet Deposition.

Lim HA, Kwon DE, Park PJ, Bin BH, Kim SB, Park SY, Cho KH, Jang DJ*, Kim ST*.

J Nanosci Nanotechnol. 2021 Jul 1;21(7):4089-4092

41. Analysis and Reproduction of Fragrance Components of Lavandula Angustifolia Flower and Essential Oil.

Ko E.S., Kim H.M., Kwak B.M., Lee MG*, & Bin, BH*

J Soc Cosmet Sci Korea. Vol 47 No 2 June 2021, 93-98.

40. A Study on the Effect of Pigments used in Cosmetic Manufacturing on the Form of Water Dispersible Formulations.

Kim HJ, Oh JW, Kwak BM, Lee MG*, Bin BH*

J Soc Cosmet Sci Korea. Vol. 47 No 1 March 2021, 41-48.

39. A Study on the Influence of Blending Ratio of Powder and Oil on the Stability of Talc-Free Pressed Powder Formulation.

Oh JW, Kim HJ, Kwak BM, Jo HT, Lee MG*, Bin BH*

J Soc Cosmet Sci Korea. Vol. 47 No 1 March 2021, 31-40.

38. Non pharmacological high-intensity ultrasound treatment of human dermal fibroblasts to accelerate wound healing.

Lee JY*, Min DJ, Kim W, Bin BH, Kim K, Cho EG*.

Sci Rep. 2021 Jan 28;11(1):2465.

37. α-Pinene Enhances the Anticancer Activity of Natural Killer Cells via ERK/AKT Pathway.

Jo HT, Cha BS, Kim HN, Brito S, Kwak BM, Kim ST, Bin BH*, Lee MG*.

Int J Mol Sci. 2021 Jan 11;22(2):E656. 

36. Ginsenoside 20(S)-protopanaxadiol induces cell death in human endometrial cancer cells via apoptosis.

Jo HT, Jang DM, Park SK, Lee MG, Cha BS, Park CW, Shin YS, Park HI, Baek JM, Heo HJ, Brito S, Hwan HG, Chae SH, Yan SW, Lee CH, Min CK*, Bin BH*

J Ginseng Res. 2021 Jan;45(1):126-133.


35. A Study on Factors Affecting the Effect of Blue Light Blocking in Sunscreen.

Park SJ, Kwak BM, Lee MG*, Bin BH*

J Soc Cosmet Sci Korea. Vol.46 No.4 December 2020, 383-390.

 

34. Effect of Konjac Glucomannan (KGM) on the Reconstitution of the Dermal Environment against UVB-Induced Condition.

Choi KH, Kim ST, Bin BH*, Park PJ*

Nutrients. 2020 Sep 11;12(9):E2779.

33. Implication of the zinc-epigenetic axis in epidermal homeostasis.

Lee MG, Chae S, Nakajima K, Ibi M, Sano H, Hara T, Jo H, Takagishi T, Cha B, Baek JM, Yoshigai E, Ohashi T, Irié T, Sano S, Lee JS, Fukada T*, Bin BH*

J Dermatol Sci. 2020 Jun;98(3):203-206.

32. Topical Delivery of Coenzyme Q10-Loaded Microemulsion for Skin Regeneration.

Ryu KA, Park PJ, Kim SB, Bin BH, Jang DJ, Kim ST*.

Pharmaceutics. 2020 Apr 7;12(4):E332.

 

31. Zinc and Its Transporters in Epigenetics.

Brito S, Lee MG, Bin BH*, Lee JS*

Mol Cells. 2020 Apr 30;43(4):323-330 doi: 10.14348/molcells.2020.0026.

30. Possible involvement of zinc transporter ZIP10 in atopic dermatitis.

Nakajima K, Lee MG, Bin BH, Hara T, Takagishi T, Chae S, Sano S*, Fukada T*.

J Dermatol. 2020 Feb;47(2):e51-e53. (아토피 피부염에서 아연 운송체의 중요성 제시)

 

29. Loss of the dermis zinc transporter ZIP13 promotes the mildness of fibrosarcoma by inhibiting autophagy.

Lee MG, Choi MA, Chae S, Kang MA, Jo H, Baek JM, In KR, Park H, Heo H, Jang D, Brito S, Kim ST, Kim DO, Lee JS, Kim JR*, Bin BH*

Sci Rep. 2019 Oct 21;9(1):15042. 

28. Different Actions of Intracellular Zinc Transporters ZIP7 and ZIP13 Are Essential for Dermal Development.

Lee MG, Bin BH*

Int J Mol Sci. 2019 Aug 13;20(16).

27. The epithelial zinc transporter ZIP10 epigenetically regulates human epidermal homeostasis by modulating histone acetyltransferase activity.

Bin BH, Lee SH, Bhin J, Irié T, Kim S, Seo J, Mishima K, Lee TR, Hwang D, Fukada T, Cho EG*.

Br J Dermatol. 2019 Apr;180(4):869-880. 

26. Staphylococcus aureus-derived extracellular vesicles induce monocyte recruitment by activating human dermal microvascular endothelial cells in vitro.

Kim J, Bin BH, Choi EJ, Lee HG, Lee TR*, Cho EG*.

Clin Exp Allergy. 2019 Jan;49(1):68-81.

 

25. Function, structure and transport aspects of ZIP and ZnT zinc transporters in immune cells.

Bin BH*, Seo J, Kim ST*.

J Immunol Res. 2018 Oct 2;2018:9365747.

24. The Role of the Slc39a Family of Zinc Transporters in Zinc Homeostasis in Skin.

Bin BH*, Hojyo S, Seo J, Hara T, Takagishi T, Mishima K, Fukada T*.

Nutrients. 2018 Feb 16;10(2).

23. Exposure of human melanocytes to UVB twice and subsequent incubation leads to cellular senescence and senescence-associated pigmentation through the prolonged p53 expression.

Choi SY, Bin BH, Kim W, Lee E, Lee TR, Cho EG*.

J Dermatol Sci. 2018 Jun;90(3):303-312.

 

22. Requirement of zinc transporter ZIP10 for epidermal development: implication of the ZIP10-p63 axis in epithelial homeostasis.

Bin BH*, Bhin J, Takaishi M, Toyoshima KE, Kawamata S, Ito K, Hara T, Watanabe T, Irié T, Takagishi T, Lee SH, Jung HS, Rho S, Seo J, Choi DH, Hwang D, Koseki H, Ohara O, Sano S, Tsuji T, Mishima K, Fukada T*.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12243-12248.

21. Synergistic effect of maltose enhances the anti-melanogenic activity of acarbose

Bin BH, Kim ST, Bhin J, Byoun K, Lee TR*, Cho EG*.

Arch Dermatol Res. 2017 Apr;309(3):217-223.

20. Requirement of Zinc Transporter SLC39A7/ZIP7 for Dermal Development to Fine-Tune Endoplasmic Reticulum Function by Regulating Protein Disulfide Isomerase.

Bin BH*, Bhin J, Seo J, Kim SY, Lee E, Park K, Choi DH, Takagishi T, Hara T, Hwang D, Koseki H, Asada Y, Shimoda S, Mishima K, Fukada T*.

J Invest Dermatol. 2017 Aug;137(8):1682-1691. 

19. An acrodermatitis enteropathica-associated Zn transporter, ZIP4, regulates human epidermal homeostasis.

Bin BH, Bhin J, Kim NH, Lee SH, Jung HS, Seo J, Kim DK, Hwang D, Fukada T, Lee AY, Lee TR*, Cho EG*.

J Invest Dermatol. 2017 Apr;137(4):874-883. 

18. Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression.

Fukunaka A, Fukada T, Bhin J, Suzuki L, Tsuzuki T, Takamine Y, Bin BH, Yoshihara T, Ichinoseki-Sekine N, Naito H, Miyatsuka T, Takamiya S, Sasaki T, Inagaki T, Kitamura T, Kajimura S, Watada H, Fujitani Y*.

PLoS Genet. 2017 Aug 30;13(8):e1006950.

17. ITAC induces the melanocytic migration and hypopigmentation through destabilizing p53 via HDAC5: A possible role of ITAC in pigment-related disorders.

Lee E, Choi SY, Bin BH, Kim NH, Kim KH, Choi DH, Han J, Choi H, Lee AY, Lee TR*, Cho EG*.

Br J Dermatol. 2017 Jan;176(1):127-137. 

 

16. Fibronectin-Containing Extracellular Vesicles Protect Melanocytes Against Ultraviolet Radiation-Induced Cytotoxicity.

Bin BH, Kim DK, Kim NH, Choi EJ, Bhin J, Kim ST, Gho YS, Lee AY, Lee TR*, Cho EG*.

J Invest Dermatol. 2016 May;136(5):957-66. 

15. The development of sugar-based anti-melanogenic agents.

Bin BH, Kim ST, Bhin J, Lee TR*, Cho EG*.

Int J Mol Sci. 2016 Apr 16;17(4). 

14. S100A7 (psoriasin) inhibits human epidermal differentiation by enhanced IL-6 secretion through IκB/NF-κB signaling.

Son ED, Kim HJ, Kim KH, Bin BH, Bae IH, Lim KM, Yu SJ, Cho EG*, Lee TR*.

Exp Dermatol. 2016 Aug;25(8):636-41. 

13. Jak1 tyrosine kinase hyperactivation induces stepwise progressive pruritic dermatitis.

Yasuda T, Fukada T, Nishida K, Nakayama M, Matsuda M, Miura I, Dainichi T, Fukuda S, Kabashima K, Nakaoka S, Bin BH, Kubo M, Ohno H, Hasegawa T, Ohara O, Koseki H, Wakana S, Yoshida H*.

J Clin Invest. 2016 Jun 1;126(6):2064-76. doi: 10.1172/JCI82887. Epub 2016 Apr 25.

12. Membrane-Associated Transporter Protein (MATP) regulates melanosomal pH and influences tyrosinase activity.

Bin BH, Bhin J, Yang SH, Choi DH, Cho EG*, Lee TR*.

PLoS One. 2015 Jun 9;10(6):e0129273.

 

11. Spondylocheirodysplastic Ehlers-Danlos syndrome (SCD-EDS) and the mutant zinc transporter ZIP13

Bin BH, Hojyo S, Lee TR*, Fukada T*.

Rare Dis. 2014 Dec 1:2(1), e974982.

10. Molecular pathogenesis of Spondylocheirodysplastic Ehlers-Danlos syndrome caused by mutant ZIP13 proteins.

Bin BH, Hojyo S, Hosaka T, Bhin J, Kano H, Miyai T, Ikeda M, Kimura-Someya T, Shirouzu M, Cho EG, Fukue K, Kambe T, Ohashi W, Kim KH, Seo J, Choi DH, Nam YJ, Hwang D, Fukunaka A, Fujitani Y, Yokoyama S, Superti-Furga A, Ikegawa S, Lee TR*, Fukada T*.

EMBO Mol Med. 2014 Jul 9;6(8):1028-42.

9. Hyperosmotic stress reduces melanin production by altering melanosome formation.

Bin BH, Bhin J, Yang SH, Choi DH, Park K, Shin DW, Hwang D, Cho EG*, Lee TR*.

PLoS One. 2014 Aug 29;9(8):e105965.

8. Novel inhibitory effect of N-(2-hydroxycyclohexyl)valiolamine on melanin production in a human skin model.

Bin BH, Joo YH, Lee AY, Shin SS, Cho EG*, Lee TR*.

Int J Mol Sci. 2014 Jul 9;15(7):12188-95.

7. The zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B cell receptor signal strength.

Hojyo S, Miyai T, Fujishiro H, Kawamura M, Yasuda T, Hijikata A, Bin BH, Nakayama M, Ohara O, Himeno SI, Yoshida H, Koseki H, Fukada T*.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11786-91. 

6. The zinc transporter SLC39A10/ZIP10 facilitates anti-apoptotic signaling during early B cell development.

Miyai T, Hojyo S, Ikawa T, Kawamura M, Irie T, Ogura H, Hijikata A, Bin BH, Yasuda T, Kitamura H, Nakayama M, Ohara O, Yoshida H, Koseki H, Mishima K, Fukada T*.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11780-5.

5. Novel method for isolating human melanoblasts from keratinocyte culture.

Cho EG, Bin BH, Choi H, Park PJ, Kang HH, Lee TR*.

Pigment Cell Melanoma Res. 2014 May; 27(3): 489-94.

4. Novel inhibitory function of miR-125b in melanogenesis.

Kim KH, Bin BH, Kim J, Dong SE, Park PJ, Choi H, Kim BJ, Yu SJ, Kang H, Kang HH, Cho EG, Lee TR*.

Pigment Cell Melanoma Res. 2014 Jan;27(1):140-4.

 

3. Novel inhibitory effect of the antidiabetic drug voglibose on melanogenesis.

Bin BH, Seo J, Yang SH, Lee E, Choi H, Kim KH, Cho EG*, Lee TR*.

Exp Dermatol. 2013 Aug;22(8):541-6.

 

2. Biochemical characterization of human ZIP13 protein: a homo-dimerized zinc transporter involved in the spondylocheiro dysplastic Ehlers-Danlos syndrome.

Bin BH, Fukada T, Hosaka T, Yamasaki S, Ohashi W, Hojyo S, Miyai T, Nishida K, Yokoyama S, Hirano T*.

J Biol Chem. 2011 Nov 18;286(46):40255-65.

1. The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth.

Hojyo S, Fukada T, Shimoda S, Ohashi W, Bin BH, Koseki H, Hirano T*.

PLoS One. 2011 Mar 22;6(3):e18059.

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